Rapid detection of pathogens using lyotropic liquid crystals
| Autor: | Manuel Caño-García, X. Quintana, José Manuel Otón, Morten Andreas Geday, José Miguel Escolano, Eva Otón |
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| Rok vydání: | 2019 |
| Předmět: |
Liposome
Telecomunicaciones Materials science business.industry Matemáticas Nanotechnology 02 engineering and technology 021001 nanoscience & nanotechnology 01 natural sciences Micelle Atomic and Molecular Physics and Optics 010309 optics Membrane Optics Liquid crystal Lyotropic liquid crystal 0103 physical sciences Electrónica Naked eye 0210 nano-technology business Biosensor Macromolecule |
| Zdroj: | Optics Express, ISSN 1094-4087, 2019, Vol. 27, No. 7 Archivo Digital UPM Universidad Politécnica de Madrid |
| ISSN: | 1094-4087 |
| Popis: | Lyotropic liquid crystals play an important role in many biological environments, such as micelles, liposomes, and phospholipid bilayers of cell membranes. In this work, we explore the performance of lyotropic liquid crystals as biosensors for macromolecules, proteins and whole microorganisms in hydrophilic media, i.e., the natural media where these specimens exist. The aim is to detect specific targets employing simple, unpowered sensors that can be used in the field, with minimum additional equipment. A number of different structures have been explored. The novelty in this work is the inclusion of a new optical effect, flow enhanced amplification, that allows for the semiquantitative detection of microscopic targets in lyotropic liquid crystal cells using the naked eye only. |
| Databáze: | OpenAIRE |
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