Specific Inhibition of Poliovirus Induced Blockade of Cell Protein Synthesis by a Thiopyrimidine Derivative
| Autor: | B. Loddo, G. P. Mereu, Maria Antonietta Marcialis, P. La Colla |
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| Rok vydání: | 1972 |
| Předmět: |
Time Factors
viruses Biology Tritium Virus Replication medicine.disease_cause Antiviral Agents Guanidines Virus Cell Line chemistry.chemical_compound Leucine Virology Protein biosynthesis medicine Humans Carboxylate Cycloheximide Laryngeal Neoplasms Uridine Cells Cultured Poliovirus Carcinoma RNA Cell protein Molecular biology Neoplasm Proteins Blockade Pyrimidines chemistry Biochemistry Cell culture Dactinomycin RNA Viral Sulfur |
| Zdroj: | Journal of General Virology. 17:13-18 |
| ISSN: | 1465-2099 0022-1317 |
| DOI: | 10.1099/0022-1317-17-1-13 |
| Popis: | Summary A thiopyrimidine derivative, i.e. ethyl-2-methylthio-4-methyl-5-pyrimidine carboxylate (S-7) is capable of preventing both poliovirus RNA synthesis and virus induced inhibition of cell protein synthesis. |
| Databáze: | OpenAIRE |
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