Confocal microscopy in a case of crystalline keratopathy in a patient with smouldering multiple myeloma
| Autor: | Cosimo Mazzotta, Stefano Caragiuli, Aldo Caporossi |
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| Rok vydání: | 2013 |
| Předmět: |
Corneal crystals
Pathology medicine.medical_specialty smouldering myeloma genetic structures In vivo confocal microscopy Confocal Confocal microscopy Corneal dystrophies Smouldering myeloma Corneal Diseases law.invention Diagnosis Differential In vivo law Cornea medicine Humans Multiple myeloma Aged corneal dystrophies Microscopy Confocal business.industry Settore MED/30 - MALATTIE APPARATO VISIVO Eye Neoplasms Dystrophy medicine.disease eye diseases Ophthalmology medicine.anatomical_structure Female sense organs Differential diagnosis Multiple Myeloma business |
| Zdroj: | International Ophthalmology. 34:651-654 |
| ISSN: | 1573-2630 0165-5701 |
| Popis: | We report the clinical and confocal microscopic findings of the cornea in a patient with smouldering multiple myeloma (SMM) using in vivo scanning laser confocal microscopy. A 72-year-old female underwent a complete ophthalmological examination including slit-lamp biomicroscopy with digital photography, HRT II laser scanning in vivo confocal microscopy and haematological laboratory assessment. Corneal biomicroscopy revealed the presence of bilateral diffuse microgranular tiny grey opacities. In vivo confocal microscopy showed randomly oriented hyper-reflective needle-shaped crystals throughout all levels of the stroma, sparing epithelium and endothelium. In vivo confocal microscopy was very helpful in the differential diagnosis by allowing the nature of the corneal deposits to be established, revealing the typical aspect of the crystals, and excluding granular dystrophy, leading to a suspected diagnosis of SMM. Crystalline corneal deposits may easily be confused as crumb-like opacities typical of granular dystrophy on slit-lamp examination even by experienced ophthalmologists. |
| Databáze: | OpenAIRE |
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