Results of Microsurgery in Cushing’s Disease and Effect on Hypertension
| Autor: | G. Niedworok, D.K. Lüdecke |
|---|---|
| Rok vydání: | 1985 |
| Předmět: |
Adenoma
Reoperation Microsurgery medicine.medical_specialty Pathology Hydrocortisone endocrine system diseases medicine.medical_treatment MEDLINE Blood Pressure Disease Paraneoplastic Endocrine Syndromes Humans Medicine Pituitary Neoplasms Pharmacology (medical) Cushing Syndrome business.industry Cushing's disease medicine.disease digestive system diseases Surgery ACTH Syndrome Ectopic stomatognathic diseases Blood pressure Hypertension Remission rate Cardiology and Cardiovascular Medicine business |
| Zdroj: | Cardiology. 72:91-94 |
| ISSN: | 1421-9751 0008-6312 |
| Popis: | In 100 consecutive transnasal sellar explorations in suspected Cushing's disease, 88 pituitary adenomas were removed. The initial remission rate in adenoma cases was about 90%. Complications related to surgery had been rare. Regularly after complete selective adenomectomy a period of ACTH and cortisol deficiency was found (90%). In these patients only 1 recurrence was seen whereas from 5 patients without cortisol deficit a relapse occurred in 4. Hypertension was found in 80% of patients with verified Cushing's disease. With normalization of cortisol excess, hypertension disappeared in 75% and was ameliorated in 15%. |
| Databáze: | OpenAIRE |
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