Beat-to-beat variability of P-wave in patients suffering from atrial fibrillation
| Autor: | Federica Censi, Eugenio Mattei, Alessandro Ricci, Giuseppe Boriani, Elisa Reggiani, Ivan Corazza, Giovanni Calcagnini |
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| Přispěvatelé: | Censi, Federica, Calcagnini, Giovanni, Mattei, Eugenio, Ricci, Alessandro, Corazza, Ivan, Reggiani, Elisa, Boriani, Giuseppe |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Bypass grafting 0206 medical engineering Biomedical Engineering Beat (acoustics) Signal Processing 1707 Health Informatics 02 engineering and technology 030204 cardiovascular system & hematology Sensitivity and Specificity 03 medical and health sciences 0302 clinical medicine Heart Conduction System Internal medicine Atrial Fibrillation Medicine Humans In patient Heart Atria Postoperative Period Coronary Artery Bypass medicine.diagnostic_test business.industry Case-control study Atrial fibrillation Models Theoretical Control subjects medicine.disease 020601 biomedical engineering medicine.anatomical_structure Cardiovascular Diseases Case-Control Studies Cardiology business Electrocardiography Artery |
| Zdroj: | EMBC |
| Popis: | The aim of this paper was to analyze the P-wave variability over time in patients suffering from Atrial Fibrillation (AF). Behind some time-domain and morphological features of the P-wave template, two novel indexes of P-wave variability have been estimated: one based on the cross-correlation coefficients among the P-waves (Correlation Index, CI), and one associated to variation of P-waves amplitude (Amplitude Index, AI). These indexes were estimated in two experimental models: patients suffering from persistent AF respect to control subjects and patients developing post-operative AF (POAF) after coronary artery bypass grafting respect to patients without POAF. The control group resulted to be characterized by shorter P-wave duration and by a less amount of fragmentation and variability, respect to AF patients (with a sensitivity and specificity of 98.4% and 95 % respectively). Also P-wave features resulted to be different for patients with POAF respect to patients without. In conclusion the quantification of the P-wave variability over time can add information in the understanding of the association between the anatomical atrial substrate and atrial arrhythmias. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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