Hydrogel Fiber Cultivation Method for Forming Bacterial Cellulose Microspheres
Autor: | Norihisa Miki, Kazuhiko Higashi |
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Jazyk: | angličtina |
Rok vydání: | 2018 |
Předmět: |
0301 basic medicine
Fabrication Materials science lcsh:Mechanical engineering and machinery Microfluidics microfluidics Nanotechnology 02 engineering and technology Article Microsphere 03 medical and health sciences chemistry.chemical_compound microcarriers monodispersity lcsh:TJ1-1570 Fiber Electrical and Electronic Engineering microfabrication emulsion microbeads microbes droplet Mechanical Engineering Microcarrier 021001 nanoscience & nanotechnology 030104 developmental biology chemistry Control and Systems Engineering Bacterial cellulose Emulsion 0210 nano-technology Microfabrication |
Zdroj: | Micromachines Micromachines, Vol 9, Iss 1, p 36 (2018) Micromachines; Volume 9; Issue 1; Pages: 36 |
ISSN: | 2072-666X |
Popis: | Forming microspheres or microbeads from nanofibrous materials has recently attracted research interest for their applications in various fields, because these structures greatly impact cellular behaviors and functions. However, conventional methods of preparing microspheres or microbeads have limitations, such as limited variety of material. Here, we propose a new fabrication process for forming a nanofibrous microsphere composed of bacterial cellulose (BC), which is synthesized through fermentation by specific bacteria. The process uses a hydrogel fiber containing spherical cavities. The bacteria encapsulated into the cavities produce BC, resulting in the formation of BC microspheres. Because of its simplicity, robustness, and cost-effectiveness, this process is promising for applications, such as in biochemical engineering and cell delivery systems. |
Databáze: | OpenAIRE |
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