Abnormal levels of antioxidant defenses in a large sample of patients with hypertensive disorders of pregnancy
| Autor: | Luis Jiménez Jiménez, Encarnación Pamies-Andréu, Ovidio Muñiz Grijalvo, Pablo Stiefel García Junco, Verónica Alfaro Lara, Salvador García Morillo, José Villar Ortiz, Antonio J Vallejo-Vaz, María Luisa Miranda Guisado |
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| Rok vydání: | 2011 |
| Předmět: |
Gestational hypertension
Adult medicine.medical_specialty Physiology Glutathione reductase Pregnancy Complications Cardiovascular medicine.disease_cause Preeclampsia Lipid peroxidation chemistry.chemical_compound Pre-Eclampsia Pregnancy Internal medicine Malondialdehyde Internal Medicine medicine Humans chemistry.chemical_classification Glutathione Peroxidase business.industry Superoxide Dismutase Glutathione peroxidase Glutathione Hypertension Pregnancy-Induced medicine.disease Catalase Lipoproteins LDL Endocrinology Glutathione Reductase chemistry Case-Control Studies Chronic Disease Hypertension Female Cardiology and Cardiovascular Medicine business Oxidative stress Biomarkers |
| Zdroj: | Hypertension research : official journal of the Japanese Society of Hypertension. 35(3) |
| ISSN: | 1348-4214 |
| Popis: | Increased levels of oxidative stress have been demonstrated in Preeclampsia in previous studies, but this finding has not been established in other hypertensive disorders in pregnancy (HDP). We measured different markers of lipid peroxidation and antioxidant defenses by spectrophotometry or enzymoimmunoanalysis in 339 pregnant women: 85 with gestational hypertension (GH), 88 chronic hypertension (CH), 104 Preeclampsia and 62 healthy pregnant control women (PCW). Lower activity of superoxide dismutase and higher levels of catalase were found in GH, CH and preeclampsia compared with PCW (964.4±116.5, 970.0±120.4, 971.2±137.5 and 1063.4±133.7 U g(-1) Hb, P |
| Databáze: | OpenAIRE |
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