The COVID-19 outbreak in Italy: Initial implications for organ transplantation programs

Autor: Angelico, Roberta, Trapani, Silvia, Manzia, Tommaso Maria, Lombardini, Letizia, Tisone, Giuseppe, Cardillo, Massimo
Rok vydání: 2020
Předmět:
Organ procurement organization
medicine.medical_specialty
Tissue and Organ Procurement
infection and infectious agents - viral
Critical Care
infectious disease
Pneumonia
Viral
organ procurement and allocation
030230 surgery
Organ transplantation
Disease Outbreaks
law.invention
Betacoronavirus
03 medical and health sciences
0302 clinical medicine
editorial/personal viewpoint
law
Pandemic
Epidemiology
Humans
donors and donation: donor-derived infections
Immunology and Allergy
Medicine
organ transplantation in general
Pharmacology (medical)
Intensive care medicine
Pandemics
Transplantation
SARS-CoV-2
business.industry
critical care/intensive care management
epidemiology
health services and outcomes research
organ procurement organization
COVID-19
Outbreak
Organ Transplantation
Intensive care unit
Tissue Donors
Settore MED/18
Intensive Care Units
Italy
Infectious disease (medical specialty)
Donation
Communicable Disease Control
Quarantine
Coronavirus Infections
business
Zdroj: American Journal of Transplantation
ISSN: 1600-6135
DOI: 10.1111/ajt.15904
Popis: The spread of Coronavirus Disease 2019 (COVID-19) has already reached a pandemic dimension within a few weeks. Italy has been one of the first countries dealing with the outbreak of COVID-19, and severe measures have been adopted to limit viral transmission. The spread of COVID-19 may have several implications in organ transplant activity that physicians should be aware of. The initial experience gained during the COVID-19 outbreak shows that around 10% of infected patients in Italy need intensive care management to overcome the acute respiratory distress syndrome. Due to the exponential rise of infected patients we are now facing an actual risk of saturation of intensive care unit (ICU) beds. A restriction in the number of ICU beds available for both donors and transplant recipients may unfavorably influence the overall donation activity, and eventually lead to a reduced number of transplants. Preliminary Italian data show that a 25% reduction of procured organs has already occurred during the first 4 weeks of COVID-19 outbreak. This underlines the need to closely monitor what will be further happening in ICUs due to the COVID-19 spread in the attempt to preserve transplant activity, especially in Western countries where deceased donors represent the major organ resource.
Databáze: OpenAIRE
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