Congenital high airway obstruction syndrome (CHAOS): discussing the role and limits of prenatal diagnosis starting from a single-center case series
| Autor: | Maria Diletta, D'Eufemia, Stefano, Cianci, Filippo, Di Meglio, Letizia, Di Meglio, Lavinia, Di Meglio, Salvatore Giovanni, Vitale, Antonio Simone, Laganà, Benito, Chiofato, Agnese Maria Chiara, Rapisarda, Francesco, Padula, Valentina, La Rosa, Claudio, Coco, Carmine, Vascone |
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| Rok vydání: | 2017 |
| Předmět: |
Pediatrics
medicine.medical_specialty Fetus prenatal diagnosis diagnosis business.industry Autopsy Prenatal diagnosis Review Article Airway obstruction Single Center medicine.disease 03 medical and health sciences 0302 clinical medicine In utero Laryngeal Atresia Ascites medicine prognosis 030216 legal & forensic medicine medicine.symptom congenital high airway obstruction business 030217 neurology & neurosurgery |
| Zdroj: | Journal of prenatal medicine. 10(1-2) |
| ISSN: | 1971-3282 |
| Popis: | OBJECTIVES we aimed to report our experience about congenital high airway obstruction syndrome (CHAOS) that is a rare and fatal congenital anomaly; laryngeal atresia is the most frequent cause. Sonographic findings are enlarged echogenic lungs, dilated trachea, and ascites. METHODS we performed a single-center case series analysis collecting antenatally through ultrasound examination, and some of them confirmed by autopsy. RESULTS we report six cases of CHAOS diagnosed by antenatal ultrasonography between 2007 and 2013. CONCLUSION to date literature provides very few individual case reports. This work describes typical sonographic findings of this syndrome and it underlines the importance of early prenatal diagnosis to improve prognosis thought an ex utero intrapartum treatment, that seems to be the only chance of survival for the affected fetus. |
| Databáze: | OpenAIRE |
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