Cationic DMPC/DMTAP Lipid Bilayers: Local Lateral Polarization of Phosphatidylcholine Headgroups
| Autor: | Masahito Yamazaki, Victor Levadny |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Models
Molecular Stereochemistry Bilayer Lipid Bilayers Molecular Conformation Cationic polymerization Phospholipid Surfaces and Interfaces Condensed Matter Physics Mole fraction chemistry.chemical_compound Molecular dynamics Crystallography chemistry Cations Phosphatidylcholine Phosphatidylcholines Electrochemistry Molecule General Materials Science Dimyristoylphosphatidylcholine Lipid bilayer Spectroscopy |
| Zdroj: | Langmuir. 21:5677-5680 |
| ISSN: | 1520-5827 0743-7463 |
| Popis: | We investigated the effect of dimyristoyltrimethylammonium propane (DMTAP) charge on area per molecule of mixed DMTAP/dimyristoylphosphatidylcholine (DMPC) bilayers in a simple model. Assuming that trimethylammonium (TAP) charge causes lateral polarization of neighboring PC molecules, we analyzed variation in area per molecule as the mole fraction of TAP increases. The theoretical predictions obtained in the present study are consistent with results of a recent molecular dynamics simulation study (Gurtovenko et al. Biophys. J. 2004, 86, 3461). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|