Intra-articular injections of botulinum toxin a for refractory joint pain: a systematic review and meta-analysis
Autor: | Ye Ye, Jian-hua Li, Hai-xin Song, Yan Dong, Tao Wu |
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Rok vydání: | 2016 |
Předmět: |
0301 basic medicine
medicine.medical_specialty WOMAC Physical Therapy Sports Therapy and Rehabilitation Osteoarthritis Injections Intra-Articular Botulinum toxin a law.invention 03 medical and health sciences 0302 clinical medicine Randomized controlled trial Refractory law Internal medicine Outcome Assessment Health Care medicine Humans Botulinum Toxins Type A Pain Measurement business.industry Rehabilitation medicine.disease Arthralgia Botulinum toxin Pain Intractable Surgery 030104 developmental biology Neuromuscular Agents Meta-analysis Joint pain medicine.symptom business 030217 neurology & neurosurgery medicine.drug |
Zdroj: | Clinical Rehabilitation. 31:435-443 |
ISSN: | 1477-0873 0269-2155 |
DOI: | 10.1177/0269215516644951 |
Popis: | Objective:To assess the benefit of intra-articular injection of Botulinum toxin A (BoNT-A) for chronic refractory joint pain regardless of joint or pathology.Data sources:The search was performed on Ovid MEDLINE(R) In-Process and Other Non-Indexed Citations, Ovid MEDLINE(R), Ovid EMBASE, Web of Science, and Scopus inception through Week 12, 2016.Trial selection:Clinical randomized controlled trials that evaluated BoNT-A intra-articular injection in patients with refractory joint pain were included.Data extraction:Two independent reviewers conducted data extraction.Results:A total of 6 out of 284 records were included. The analysis indicated that a statistically significant decreased pain score was found in BoNT-A therapy group than control group with WMD=1.10 (95% CI: 0.35 to 1.85; P |
Databáze: | OpenAIRE |
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