Intra-articular injections of botulinum toxin a for refractory joint pain: a systematic review and meta-analysis

Autor: Ye Ye, Jian-hua Li, Hai-xin Song, Yan Dong, Tao Wu
Rok vydání: 2016
Předmět:
Zdroj: Clinical Rehabilitation. 31:435-443
ISSN: 1477-0873
0269-2155
DOI: 10.1177/0269215516644951
Popis: Objective:To assess the benefit of intra-articular injection of Botulinum toxin A (BoNT-A) for chronic refractory joint pain regardless of joint or pathology.Data sources:The search was performed on Ovid MEDLINE(R) In-Process and Other Non-Indexed Citations, Ovid MEDLINE(R), Ovid EMBASE, Web of Science, and Scopus inception through Week 12, 2016.Trial selection:Clinical randomized controlled trials that evaluated BoNT-A intra-articular injection in patients with refractory joint pain were included.Data extraction:Two independent reviewers conducted data extraction.Results:A total of 6 out of 284 records were included. The analysis indicated that a statistically significant decreased pain score was found in BoNT-A therapy group than control group with WMD=1.10 (95% CI: 0.35 to 1.85; P
Databáze: OpenAIRE