Quantitative laryngeal electromyography: Turns and amplitude analysis
| Autor: | Melissa McCarty Statham, Clark A. Rosen, Sanjeev D. Nandedkar, Michael C. Munin |
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| Rok vydání: | 2010 |
| Předmět: |
Male
medicine.medical_specialty Laryngology Electromyography Audiology Standard deviation Recurrence Humans Medicine Vocal cord paralysis Retrospective Studies medicine.diagnostic_test business.industry Regression analysis Middle Aged medicine.disease Confidence interval Amplitude Otorhinolaryngology Case-Control Studies Motor unit recruitment Regression Analysis Female business Vocal Cord Paralysis Muscle Contraction |
| Zdroj: | The Laryngoscope. 120:2036-2041 |
| ISSN: | 0023-852X |
| DOI: | 10.1002/lary.21046 |
| Popis: | Objectives: Laryngeal electromyography (LEMG) is primarily a qualitative examination, with no standardized approach to interpretation. The objectives of our study were to establish quantitative norms for motor unit recruitment in controls and to compare with interference pattern analysis in patients with unilateral vocal fold paralysis (VFP). Design: Retrospective case-control study Methods: We performed LEMG of the thyroarytenoid-lateral cricoarytenoid muscle complex (TA-LCA) in 21 controls and 16 patients with unilateral VFP. Our standardized protocol used a concentric needle electrode with subjects performing variable force TA-LCA contraction. To quantify the interference pattern density, we measured turns and mean amplitude per turn for ≥10 epochs (each 500 milliseconds). Logarithmic regression analysis between amplitude and turns was used to calculate slope and intercept. Standard deviation was calculated to further define the confidence interval, enabling generation of a linear-scale graphical "cloud" of activity containing >90% of data points for controls and patients. Results: Median age of controls and patients was similar (50.7 vs. 48.5 years). In controls, TA-LCA amplitude with variable contraction ranged from 140--1112 μV, and regression analysis comparing mean amplitude per turn to root-mean-square amplitude demonstrated high correlation (R = 0.82). In controls performing variable contraction, median turns per second was significantly higher compared to patients (450 vs. 290, P = .002). Conclusions: We first present interference pattern analysis in the TA-LCA in healthy adults and patients with unilateral VFP. Our findings indicate that motor unit recruitment can be quantitatively measured within the TA-LCA. Additionally, patients with unilateral VFP had significantly reduced turns when compared with controls. |
| Databáze: | OpenAIRE |
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