Cognitive Impairments in Early-Detoxified Alcohol-Dependent Inpatients and Their Associations with Socio-Demographic, Clinical and Psychological Factors: An Exploratory Study

Autor: Caterina Pistarini, Marcella Ottonello, Stefano Caneva, Elena Fiabane, Elisa Torselli, Paola Spigno
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Neuropsychiatric Disease and Treatment
ISSN: 1178-2021
Popis: Stefano Caneva,1 Marcella Ottonello,1 Elisa Torselli,1,2 Caterina Pistarini,3 Paola Spigno,1 Elena Fiabane1,4 1Department of Physical and Rehabilitation Medicine, ICS Maugeri Spa SB, Institute of Genoa Nervi, Genoa, Italy; 2Miller Institute for Behavioral and Cognitive Therapy, Genoa, Italy; 3Department of Physical and Rehabilitation Medicine, ICS Maugeri Spa SB, Scientific Institute of Pavia, Genoa, Italy; 4Department of Brain and Behavioral Sciences, University of Pavia, Pavia, ItalyCorrespondence: Caterina PistariniDepartment of Physical & Rehabilitation Medicine, ICS Maugeri Spa SB, Institute of Pavia, Via Maugeri 4, Pavia, Genoa 27100, ItalyTel +39 010 30791250Fax +39 010 3079 1269Email caterina.pistarini@icsmaugeri.itPurpose: Cognitive impairment is common among patients with alcohol use disorder (AUD). However, neuropsychological assessment is not usually included as routine practice in alcohol rehabilitation programs. The aim of this study was to describe qualitatively the cognitive deficits in early-detoxified AUD patients undergoing rehabilitation and to explore relevant associations with socio-demographic, clinical and psychological factors.Patients and Methods: Forty-one patients with a diagnosis of AUD were consecutively recruited from a residential rehabilitation hospital in Northern Italy. Cognitive impairment was assessed using the Brief Neuropsychological Examination 2 (ENB-2). Anxiety, depression and severity of alcohol dependence were also evaluated using validated self-report questionnaires. Alcohol relapse was investigated 1 month after discharge.Results: Overall, 31.7% of AUD patients showed cognitive impairments according to the global score scale. However, 70.7% had an impaired performance on at least one test of the ENB-2, with particular regard to executive function, visuospatial and memory domains. Age, education and abstinence at admission were the most relevant factors associated with cognitive deficits in this clinical population.Conclusion: The detection of cognitive impairments is essential in order to adapt alcohol rehabilitation treatment to patients with cognitive deficits and enhance clinical outcomes.Keywords: neuropsychological functioning, alcohol use disorder, alcohol detoxification, rehabilitation, relapse
Databáze: OpenAIRE