Assessment of exposure to arsenic among smelter workers: A five-year follow-up
| Autor: | Bo Zetterlund, Birgitta Json Lagerkvist |
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| Rok vydání: | 1994 |
| Předmět: |
Adult
Male medicine.medical_specialty Sensory Receptor Cells Physiology chemistry.chemical_element Air Pollutants Occupational Significant negative correlation Synaptic Transmission Arsenicals Nerve conduction velocity Arsenic Occupational medicine Arsenic Trioxide Risk Factors Occupational Exposure Reaction Time medicine Humans Peripheral Nerves Adverse effect ARSENIC EXPOSURE Aged Motor Neurons Electromyography business.industry Public Health Environmental and Occupational Health Five year follow up Peripheral Nervous System Diseases Oxides Middle Aged Surgery Occupational Diseases chemistry Toxicity business Follow-Up Studies |
| Zdroj: | American Journal of Industrial Medicine. 25:477-488 |
| ISSN: | 1097-0274 0271-3586 |
| Popis: | In a group of 43 smelter workers exposed to inorganic arsenic dust for 13-45 years, nerve conduction velocities (NCVs) were significantly lower in two peripheral nerves as compared with matching referents. With multivariate data analysis, a significant negative correlation was found between cumulative absorption of arsenic and NCV in four examined nerves and the sural amplitude. Clinical symptoms of neuropathy and other symptoms related to arsenic exposure were moderate, though the difference between the groups was significant. The mean total absorption of arsenic was calculated to be less than 5 g, and the maximal absorption about 20 g. These data indicate that the adverse effect of arsenic on the peripheral nerves is dependent on long-term exposure rather than on short-term fluctuations in exposure levels. © 1994 Wiley-Liss, Inc. |
| Databáze: | OpenAIRE |
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