Control Status of Atherosclerotic Cardiovascular Risk Factors Among Japanese High-Risk Subjects:Analyses of a Japanese Health Check Database from 2008 to 2011

Autor: Toshiki Moriyama, Kunihiro Yamagata, Kenjiro Kimura, Ichiei Narita, Shouichi Fujimoto, Motoei Kunimi, Kazuhisa Tsukamoto, Masahide Kondo, Yasuo Ohashi, Tsuyoshi Watanabe, Kazuhiko Tsuruya, Kunitoshi Iseki, Tsuneo Konta, Koichi Asahi, Koji Hasegawa
Rok vydání: 2016
Předmět:
Adult
Male
medicine.medical_specialty
Time Factors
Databases
Factual
Cardiovascular risk factors
Blood Pressure
Coronary Artery Disease
030204 cardiovascular system & hematology
Health check
Coronary artery disease
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Japan
Risk Factors
Internal medicine
Diabetes mellitus
Internal Medicine
medicine
Humans
030212 general & internal medicine
Triglycerides
Aged
Glycated Hemoglobin
Cholesterol
business.industry
Biochemistry (medical)
Cholesterol
HDL
Cholesterol
LDL
Middle Aged
medicine.disease
Atherosclerosis
Cerebrovascular Disorders
Blood pressure
chemistry
Time course
lipids (amino acids
peptides
and proteins)
Female
Original Article
Glycated hemoglobin
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Cardiology and Cardiovascular Medicine
business
Zdroj: J Atheroscler Thromb
ISSN: 1880-3873
Popis: Aims Several guidelines propose target levels (TLs) of atherosclerotic risk factors (ARFs) to reduce atherosclerotic cardiovascular diseases; however, few data are available regarding the attainment statuses of TLs in Japan. In this study, utilizing the data obtained from the annual "Specific Health Check and Guidance in Japan" conducted from 2008 to 2011 (approximately 280,000 subjects each year), we determined TL attainments of ARFs in cardiovascular high-risk subjects. Methods Those who had suffered from cerebrovascular disease (pCVD) or coronary heart disease (pCHD) or were receiving diabetes mellitus treatment (DM) were selected, and the rates of subjects that attained TLs of blood pressure (BP), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), triglycerides (TGs) and glycated hemoglobin (HbA1c) were analyzed. Results Approximately 70% of pCVD or pCHD and 35% of subjects with DM attained TLs of BP. With regard to HbA1c, ＞90% of pCVD or pCHD and approximately 50% of subjects with DM attained TLs. With regard to LDL-C, ＜25% of pCHD females and approximately 35% of pCHD males and 50%-55% of subjects with pCVD or DM attained TLs. The TL-attainment rates of HDL-C and TGs were approximately 90% and 75%, respectively, for the three diseases. Analyses of time course changes in their attainment statuses revealed that the attainment rates of BP and LDL-C significantly improved in all the diseases. Conclusions TL-attainment rates of BP and LDL-C were not as high as those for HDL-C, TGs, and HbA1c; however, they both showed highly significant improvements during the study period.
Databáze: OpenAIRE
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