Occult pancreatobiliary reflux in patients with a normal pancreaticobiliary junction
| Autor: | Nobuhiro Sato, Hiroyuki Tadokoro, Yoshito Iida, Yoshihiro Kubokawa, Tadayuki Maehara, Jin Kan Sai, Kuniaki Kojima, Masafumi Suyama |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Gallbladder Diseases Gastroenterology Secretin Internal medicine medicine Carcinoma Bile Humans Radiology Nuclear Medicine and imaging Cholangiopancreatography Endoscopic Retrograde Pancreatic duct business.industry Gallbladder Bile Reflux Pancreatic Ducts Reflux Middle Aged medicine.disease Magnetic Resonance Imaging medicine.anatomical_structure Pancreaticobiliary maljunction Biliary tract Amylases Pancreatic juice Female Gallbladder Neoplasms Cholecystectomy Bile Ducts business |
| Zdroj: | Gastrointestinal Endoscopy. 57:364-368 |
| ISSN: | 0016-5107 |
| Popis: | Background: The aim of this study was to investigate pancreatobiliary reflux in individuals with a normal pancreaticobiliary junction. Methods: Seventy-four patients with a normal pancreaticobiliary junction, as determined by ERCP, underwent secretin injection MRCP before cholecystectomy. Based on changes in the diameter of the biliary system after secretin injection, patients were categorized into enhanced or nonenhanced groups. Results: Biliary amylase was measured in the 4 patients allocated to the enhanced group and 60 in the nonenhanced group. The mean (SD) biliary amylase level in the gallbladder was 123,723 (115,125) IU/L in the enhanced group and 238 (507) IU/L in the nonenhanced group (p < 0.0001). The mean (SD) biliary amylase level in gallbladders with carcinoma (n = 7) was 68,281 (106,500) IU/L, which was significantly higher than that in gallbladders without carcinoma (p < 0.01). Conclusion: Pancreatobiliary reflux similar to that seen in patients with pancreaticobiliary maljunction can occur in individuals with a normal pancreaticobiliary junction and may be associated with carcinoma of the gallbladder. Secretin injection MRCP is useful for identifying these individuals. (Gastrointest Endosc 2003;57:364-8.) |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect