Genetic Diversity among Pseudorabies Viruses Isolated from Dogs in France from 2006 to 2018
| Autor: | Marie-Frédérique Le Potier, Gaëlle Simon, Aurélie Oger, Céline Deblanc |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Microbiology (medical)
Genetic diversity General Immunology and Microbiology biology phylogenetic analysis Fauna Zoology Pseudorabies biology.organism_classification Article Virus Infectious Diseases Wild boar gC encoding region pseudorabies biology.animal Genotype Immunology and Allergy hunting dog Clade Molecular Biology Gene Aujeszky’s disease wild boar |
| Zdroj: | Pathogens Volume 8 Issue 4 |
| ISSN: | 2076-0817 |
| Popis: | Pseudorabies (PR), also known as Aujeszky&rsquo s disease, is an economically important disease for the pig industry. It has been eradicated in domestic pigs in many European countries, including France, but its causative agent&mdash Suid Herpesvirus 1&mdash is still circulating in wild boars. The risk of endemic PR in wild fauna lies in reintroducing the virus among domestic pigs and transmitting it to other mammals, especially hunting dogs for which the disease is rapidly fatal. As such infections are regularly reported in France, this study genetically characterized canine PR virus strains in the country to obtain information on their diversity and evolution. Partial sequencing of the glycoprotein C-encoding gene from 55 virus strains isolated from dogs between 2006 and 2018 showed that 14 strains belonged to genotype I-clade A and another 38 to genotype I-clade B, two clades usually reported in Western Europe. More surprisingly, three strains were found to belong to genotype II, suggesting an Asian origin. Genotype I-clade A strains exhibited the highest diversity as five geographically segregated genogroups were identified. |
| Databáze: | OpenAIRE |
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