Esterase-sensitive trithiane-based hydrogen sulfide donors
| Autor: | Ming Xian, Clovis Shyaka, Chung-Min Park |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
chemistry.chemical_classification
010405 organic chemistry Hydrogen sulfide Organic Chemistry equipment and supplies 010402 general chemistry 01 natural sciences Biochemistry Medicinal chemistry Esterase 0104 chemical sciences chemistry.chemical_compound Enzyme chemistry Enzymatic hydrolysis Physical and Theoretical Chemistry Methylene |
| Zdroj: | Organicbiomolecular chemistry. 17(47) |
| ISSN: | 1477-0539 |
| Popis: | 1,3,5-Trithiane functionalized with esterase-sensitive ester groups on the methylene linkers was developed as a class of enzymatic hydrolysis-based hydrogen sulfide (H2S) donors. The amount of H2S released from the donors was dependent on the number of ester bonds. The donors release H2S in a controllable manner in the presence of an enzyme. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|