Optimal Endoscopic Screening Interval for Early Detection of Gastric Cancer: a Single-Center Study
| Autor: | Yong Hwan Kwon, Su Youn Nam, Seong Woo Jeon, Sang Jik Lee, Seong Jae Yeo, Sun Jin, Sang Hoon Kwon |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Time Factors Early detection Antineoplastic Agents Endoscopic Screening Single Center 03 medical and health sciences 0302 clinical medicine Stomach Neoplasms Gastroscopy Odds Ratio Medicine Mass Screening Humans Prospective Studies Prospective cohort study Early Detection of Cancer Aged Neoplasm Staging medicine.diagnostic_test Gastroenterology & Hepatology business.industry Stomach Cancer Optimal Interval General Medicine Middle Aged medicine.disease Endoscopy Early Gastric Cancer Gastric Cancer Editorial 030220 oncology & carcinogenesis Interval (graph theory) 030211 gastroenterology & hepatology Original Article Female Radiology Endoscopic screening business |
| Zdroj: | Journal of Korean Medical Science |
| ISSN: | 1598-6357 |
| Popis: | Background The optimal endoscopic screening interval for early gastric cancer (EGC) detection still remains controversial. Thus, we performed this prospective study to clarify the optimal interval between endoscopic examinations for EGC detection. Methods A questionnaire survey for penultimate endoscopy and gastric cancer (GC) diagnosis interval was used; the findings were then analyzed. The patients were divided into two groups according to GC type and endoscopic examinations intervals. Results A total of 843 patients were enrolled. The endoscopic GC detection interval (P < 0.001), tumor location (P < 0.001), tumor size (P < 0.001), histology (P < 0.001), tumor stage (P < 0.001), and treatment modality (P < 0.001) showed significant differences in the univariate analysis between EGC and advanced gastric cancer (AGC). Endoscopic examination intervals below 2 years and 3 years were associated with higher proportions of EGC detection (adjusted odds ratio, 2.458 and 3.022, respectively) (P < 0.001). The patients with endoscopic examination to GC diagnosis interval of < 2 years showed significant differences in tumor size (P < 0.001), tumor stage (P < 0.001), and treatment modality (P < 0.001) compared to those with intervals of > 2 years and without screening. Similar results were observed in those with < 3-year intervals. Conclusion Triennial endoscopic screening might be as effective as biennial screening in increasing the detection rate of EGC and the risk of subsequent curable endoscopic resections. Graphical Abstract |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|