Prevention of secondary cases of meningococcal disease in Denmark
Autor: | S Samuelsson, Merete Osler, E. T. Hansen, B. Jeune |
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Rok vydání: | 2000 |
Předmět: |
Adult
Male medicine.medical_specialty Adolescent Epidemiology Denmark Disease Meningococcal disease Disease Transmission Infectious Humans Medicine Child Family Health Medical Audit business.industry Public health Infant Newborn Infant Questionnaire Antibiotic Prophylaxis medicine.disease Health Surveys Surgery Meningococcal Infections Vaccination Infectious Diseases Telephone interview Child Preschool Family medicine Chemoprophylaxis Female business Research Article |
Zdroj: | Epidemiology and Infection. 124:433-440 |
ISSN: | 1469-4409 0950-2688 |
DOI: | 10.1017/s0950268899003775 |
Popis: | Close contacts of cases of meningococcal disease are at increased risk of disease themselves. We identified household-like contacts of index cases, to investigate whether relevant target groups are informed, receive and follow recommended chemoprophylaxis and vaccination, and to ascertain the time delay for implementation of these measures. A telephone interview of 172 households of index cases and a questionnaire survey among 634 parents of contacts of cases in institutions were carried out. Results were compared with reports from Medical Officers of Health. In 21% of the cases, Medical Officers reported fewer household-like contacts than were identified in this study. Written information was effective. However, 59% of households, and 36% of parents of contacts in institutions felt a lack of information about how the disease is acquired, the risk and signs of illness. For household-like contacts the coverage rate for chemoprophylaxis with an appropriate drug was 90% and for vaccination 59%. No secondary cases occurred among those treated with chemoprophylaxis, but among those not treated, there were two secondary cases. The study design provided a useful audit methodology to evaluate the completeness of implementation and the success of prophylactic measures for meningococcal disease. |
Databáze: | OpenAIRE |
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