Long-Term Outcomes in Ventricular Assist Device Outflow Cannula Anastomosis to the Descending Aorta

Autor: Mustafa Özbaran, Ander Dorken Gallastegi, Sanem Nalbantgil, Çağatay Engin, Elif B. Hoşcoşkun, Tahir Yagdi, Burcu Yağmur, Umit Kahraman
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Popis: 41st Annual Meeting and Scientific Sessions of the International-Society-for-Heart-and-Lung-Transplantation (ISHLT) -- APR 24-28, 2021 -- ELECTR NETWORK
BACKGROUND Left ventricular assist device (LVAD) implantation via thoracotomy with outflow cannula anastomosis to the descending aorta is an alternative implantation technique that uses a single incision and avoids anterior mediastinal planes. We evaluated long-term survival and hospital readmissions after LVAD implantation via thoracotomy with outflow cannula anastomosis to the descending aorta. METHODS Adult patients implanted with a continuous flow centrifugal LVAD at an academic center were retrospec-tively analyzed. Patients were assigned to 1 of 2 cohorts based on the anastomosis site of the LVAD outflow cannula: ascending aorta cohort (Asc-Ao) and descending aorta cohort (Desc-Ao). Primary and secondary outcomes were sur-vival and hospital readmissions during device support. Readmission analysis included patients with double dagger 30-day survival after discharge. Multivariable analysis and propensity score matching were performed. RESULTS Survival analysis included 330 patients (Asc-Ao: 272, Desc-Ao: 58). Readmission analysis included 277 patients (Asc-Ao: 231, Desc-Ao: 46) and a total of 1028 readmissions during 654 patient-years of follow-up were analyzed. There was no significant difference in in-hospital, 6-month, 1-year, 3-year, and 5-year mortality between the two cohorts. Readmission-free survival, 30-day readmission, number of admissions per year and hospital length of stay per year were not significantly different between the 2 cohorts after adjustment for patient characteristics. CONCLUSIONS This study found no difference in long-term survival or hospital readmissions between LVAD implan-tation via thoracotomy with outflow cannula anastomosis to the descending aorta and standard implantation. (Ann Thorac Surg 2022;114:1377-85) (c) 2022 by The Society of Thoracic Surgeons
Int Soc Heart & Lung Transplantat
Databáze: OpenAIRE