Effects of omeprazole paste on healing of spontaneous gastric ulcers in horses and foals: a field trial
| Autor: | R. L. Sifferman, S. R. McClure, G. F. Ericcson, N. J. Vatistas, John E Holste, Charles G. MacAllister, J. L. Cox, G. W. White |
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| Rok vydání: | 2000 |
| Předmět: |
Male
medicine.medical_specialty Administration Oral Breeding Gastroenterology Severity of Illness Index Ointments Double-Blind Method Internal medicine Equine gastric ulcer syndrome Gastroscopy Medicine Animals Horses Stomach Ulcer Enzyme Inhibitors Omeprazole business.industry Age Factors Horse General Medicine Housing Animal digestive system diseases United States Surgery Treatment Outcome Animals Newborn Female Horse Diseases Once daily business medicine.drug Field conditions |
| Zdroj: | Equine veterinary journal. Supplement. (29) |
| Popis: | Summary A multicentre, blinded, randomised complete-block, field trial was conducted with 140 horses and foals age 4 weeks-28 years to determine if omeprazole paste is effective and safe in promoting healing of spontaneous gastric ulcers under a variety of field conditions and in different breeds and ages of horses. Horses in the study had gastric ulceration as determined by gastroscopy and were divided into replicates of 4 or 5 animals. One horse in each replicate was assigned randomly to receive an empty omeprazole syringe (sham-dosed control) and the remaining horses received omeprazole paste once daily for 28 days. Gastroscopy was repeated at the end of the study. Horses treated with omeprazole had significantly (P |
| Databáze: | OpenAIRE |
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