ACTIVATORS AND INACTIVATORS OF CALCIUM CHANNELS: EFFECTS IN THE CENTRAL NERVOUS SYSTEM
Autor: | M, Spedding, A T, Kilpatrick, B J, Alps, M, Speddings |
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Rok vydání: | 1989 |
Předmět: |
Pharmacology
Voltage-dependent calcium channel Chemistry Calcium channel Central nervous system Brain chemistry.chemical_element Calcium Calcium Channel Blockers Calcium Channel Agonists chemistry.chemical_compound medicine.anatomical_structure medicine Animals Humans Pharmacology (medical) Calcium Channels Neurotransmitter |
Zdroj: | Fundamental & Clinical Pharmacology. 3:3s-29s |
ISSN: | 1472-8206 0767-3981 |
DOI: | 10.1111/j.1472-8206.1989.tb00472.x |
Popis: | The interactions of calcium antagonists or channel activators with the different classes of calcium channel are reviewed with particular emphasis on interactions with neuronal tissue; reasons for the failure of calcium antagonists to inhibit neurotransmitter release under normal circumstances are outlined. Calcium antagonists may be protective in several pathological situations and the possibilities of protection against ischaemic damage in the central nervous system are evaluated. |
Databáze: | OpenAIRE |
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