Peripheral T-cell lymphoma in a patient with Crohn's disease

Autor: Ishmael Jaiyesimi, Srilakshmi Sudha Kollepara, Mohammad Muhsin Chisti, Seerin Viviane Shatavi
Rok vydání: 2013
Předmět:
Zdroj: BMJ case reports. 2013
ISSN: 1757-790X
Popis: A 46-year-old man with a long-standing history of Crohn’s disease who was treated with multiple therapies over a period of 9 years presented with oral lesions which on biopsy demonstrated peripheral T-cell lymphoma. Initially, the development of T-cell lymphoma was presumed to be secondary to prolonged immunosuppression but it did not respond to withholding immunosuppressive therapy. On treatment with CHOP (cyclophosphamide, hydroxydaunorubicin, oncovin and prednisone) chemotherapy, complete remission was achieved. Although development of malignancies in the immune-suppressed patient with Crohn9s disease has been previously described but we present a rare case of T-cell lymphoma in a similar patient, which has not been reported before.
Databáze: OpenAIRE