Peripheral T-cell lymphoma in a patient with Crohn's disease
Autor: | Ishmael Jaiyesimi, Srilakshmi Sudha Kollepara, Mohammad Muhsin Chisti, Seerin Viviane Shatavi |
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Rok vydání: | 2013 |
Předmět: |
Male
Pathology medicine.medical_specialty Cyclophosphamide medicine.medical_treatment Biopsy CHOP Inflammatory bowel disease Gastroenterology Article Immunocompromised Host Crohn Disease Prednisone Internal medicine hemic and lymphatic diseases Antineoplastic Combined Chemotherapy Protocols medicine Humans Chemotherapy business.industry Remission Induction Lymphoma T-Cell Peripheral Immunosuppression General Medicine Middle Aged medicine.disease Peripheral T-cell lymphoma Lymphoma Doxorubicin Vincristine business Immunosuppressive Agents medicine.drug |
Zdroj: | BMJ case reports. 2013 |
ISSN: | 1757-790X |
Popis: | A 46-year-old man with a long-standing history of Crohn’s disease who was treated with multiple therapies over a period of 9 years presented with oral lesions which on biopsy demonstrated peripheral T-cell lymphoma. Initially, the development of T-cell lymphoma was presumed to be secondary to prolonged immunosuppression but it did not respond to withholding immunosuppressive therapy. On treatment with CHOP (cyclophosphamide, hydroxydaunorubicin, oncovin and prednisone) chemotherapy, complete remission was achieved. Although development of malignancies in the immune-suppressed patient with Crohn9s disease has been previously described but we present a rare case of T-cell lymphoma in a similar patient, which has not been reported before. |
Databáze: | OpenAIRE |
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