Pcl/Chitosan Blended Nanofibrous Tubes Made by Dual Syringe Electrospinning
| Autor: | Martin Hild, Chokri Cherif, Tong Cheng, Ezzedine Laourine, Georgios Toskas, Mohammed Fayez Al Rez, Dilbar Aibibu |
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| Rok vydání: | 2015 |
| Předmět: |
nanofibrous tubes
Materials science Chemical technology technology industry and agriculture TP1-1185 macromolecular substances Polyethylene glycol poly-(£-caprolactone) polymer blend Electrospinning Chitosan chemistry.chemical_compound chemistry Chemical engineering pcl Attenuated total reflection Polycaprolactone Trifluoroacetic acid General Materials Science Polymer blend chitosan Composite material Fourier transform infrared spectroscopy electrospinning |
| Zdroj: | Autex Research Journal, Vol 15, Iss 1, Pp 54-59 (2015) |
| ISSN: | 2300-0929 |
| DOI: | 10.1515/aut-2015-0016 |
| Popis: | 3D tubular scaffolds made from Poly-(Ɛ-caprolactone) (PCL)/chitosan (CS) nanofibres are very promising candidate as vascular grafts in the field of tissue engineering. In this work, the fabrication of PCL/CS-blended nanofibrous tubes with small diameters by electrospinning from separate PCL and CS solutions is studied. The influence of different CS solutions (CS/polyethylene glycol (PEO)/glacial acetic acid (AcOH), CS/trifluoroacetic acid (TFA), CS/ AcOH) on fibre formation and producibility of nanofibrous tubes is investigated. Attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR) is used to verify the presence of CS in the blended samples. Tensile testing and pore size measurements are done to underline the good prerequisites of the fabricated blended PCL/ CS nanofibrous tubes as potential scaffolds for vascular grafts. Tubes fabricated from the combination of PCL and CS dissolved in AcOH possesses properties, which are favourable for future cell culture studies. |
| Databáze: | OpenAIRE |
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