Age related acute effects of microcystin-LR on Daphnia magna biotransformation and oxidative stress

Autor: Rafael Ortiz-Rodriguez, Claudia Wiegand
Přispěvatelé: Briand, Valerie, Leibniz Institute of Freshwater Ecology & Inland Fisheries, Ecosystèmes, biodiversité, évolution [Rennes] (ECOBIO), Centre National de la Recherche Scientifique (CNRS)-Observatoire des Sciences de l'Univers de Rennes (OSUR)-Institut Ecologie et Environnement (INEE), Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES), University of Southern Denmark (SDU), Université de Rennes (UR)-Institut Ecologie et Environnement (INEE), Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Observatoire des Sciences de l'Univers de Rennes (OSUR), Université de Rennes (UR)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Rennes 2 (UR2)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Rennes 2 (UR2)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Centre National de la Recherche Scientifique (CNRS)
Rok vydání: 2010
Předmět:
Zdroj: Toxicon
Toxicon, Elsevier, 2010, 56, pp.1342-1349
Ortiz-Rodriguez, R & Wiegand, C 2010, ' Age related acute effects of microcystin-LR on Daphnia magna biotransformation and oxidative stress ', Toxicon, vol. 56, pp. 1342–1349 .
Toxicon, 2010, 56, pp.1342-1349
ISSN: 1879-3150
0041-0101
Popis: International audience; As a result of eutrophication among other factors, bloom forming species of cyanobacteria frequently thrive and dominate communities in freshwater ecosystems. Cyanobacteria are considered as a nuisance and hazardous due to the production of toxins. The most potent and studied cyanobacterial toxins are the microcystins, especially the variant microcystin-LR (MC-LR). Daphnia magna plays a central role in freshwater pelagic food webs and its populations are negatively affected by cyanobacteria due to nutritional inadequacy, feeding interference and toxic effects on growth and reproduction. Biotransformation and antioxidant enzymes, amongst others enable D. magna capacity to cope with MC-LR up to a certain concentration. Aim of our study was to investigate the age related acute effects of MC-LR on D. magna biotransformation and antioxidant enzymes (glutathione S-transferase, GST and catalase, CAT), subsequent lipid peroxidation and furthermore to lactate and the enzyme lactate dehydrogenase (LDH). D. magna neonates (
Databáze: OpenAIRE