Pseudo-drumsticks in granulocytes of a male with a Yqh+ polymorphism
| Autor: | Ronald S. Weinger, Charleen M. Moore |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
Adult
Chromosome Aberrations Male Sex Chromosomes Secondary sex characteristic Mosaicism Neutrophils Chromosomal analysis Karyotype Hematology Biology Y chromosome Sex chromatin Molecular biology Chromosome Banding Blood smear Sex Chromatin Quinacrine Karyotyping Y Chromosome Immunology Fluorescent staining Humans Quinacrine fluorescence |
| Zdroj: | American journal of hematology. 8(4) |
| ISSN: | 0361-8609 |
| Popis: | An individual with normal male habitus, body proportions, and secondary sexual characteristics was admitted to the hospital with head trauma. A routine blood smear demonstrated that 36% of the granulocytes had "drumsticks". Chromosomal analysis revealed a 46,XYqh+ karyotype. the extremely large Y chromosome was located by quinacrine fluorescence in the "drumstick" of the polymorphonuclear granulocytes. The presence of a large Y chromosome may thus produce pseudo-drumsticks. Fluorescent staining can distinguish between true drumsticks bearing the inactive X of normal females and the pseudo-drumsticks in a normal male produced by a large Y chromosome. |
| Databáze: | OpenAIRE |
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