Human–Dromedary Camel Interactions and the Risk of Acquiring Zoonotic Middle East Respiratory Syndrome Coronavirus Infection

Autor: Pasi Penttinen, Céline M Gossner, N. Danielson, Bernard Faye, Herve Zeller, Denis Coulombier, Cornelia Adlhoch, Andrea Gervelmeyer, K. Kaasik Aaslav, F. Berthe
Přispěvatelé: Med Microbiol, Infect Dis & Infect Prev, RS: CAPHRI School for Public Health and Primary Care, RS: CAPHRI other
Rok vydání: 2014
Předmět:
Male
0301 basic medicine
Veterinary medicine
Epidemiology
Attack rate
coronavirus
Disease
Disease Vectors
L73 - Maladies des animaux
medicine.disease_cause
Interactions biologiques
MERS-CoV
SAUDI-ARABIA
Public health surveillance
Risk Factors
Maladie respiratoire
Analyse du risque
Facteur de risque
Herding
Animal Husbandry
Coronavirus
Transmission (medicine)
000 - Autres thèmes
Middle Aged
Épidémiologie
Infectious Diseases
MERS CORONAVIRUS
Middle East Respiratory Syndrome Coronavirus
Female
Original Article
Coronavirus Infections
Adult
zoonose
endocrine system
Camelus
Middle East respiratory syndrome coronavirus
Dromadaire
Biology
MERS‐CoV
Middle East
03 medical and health sciences
Maladie de l'homme
Environmental health
camels
medicine
Camel milk
Animals
Humans
Transmission des maladies
STABILITY
General Veterinary
General Immunology and Microbiology
COV
Public Health
Environmental and Occupational Health
LIVESTOCK
Étude de cas
Original Articles
zoonoses
030104 developmental biology
ANTIBODIES
Arabian Peninsula
Coronavirinae
Maps as Topic
Zdroj: Zoonoses and Public Health
Zoonoses and Public Health, 63(1), 1-9. Wiley-Blackwell
ISSN: 1863-2378
1863-1959
DOI: 10.1111/zph.12171
Popis: Summary Middle East respiratory syndrome coronavirus (MERS‐CoV) cases without documented contact with another human MERS‐CoV case make up 61% (517/853) of all reported cases. These primary cases are of particular interest for understanding the source(s) and route(s) of transmission and for designing long‐term disease control measures. Dromedary camels are the only animal species for which there is convincing evidence that it is a host species for MERS‐CoV and hence a potential source of human infections. However, only a small proportion of the primary cases have reported contact with camels. Other possible sources and vehicles of infection include food‐borne transmission through consumption of unpasteurized camel milk and raw meat, medicinal use of camel urine and zoonotic transmission from other species. There are critical knowledge gaps around this new disease which can only be closed through traditional field epidemiological investigations and studies designed to test hypothesis regarding sources of infection and risk factors for disease. Since the 1960s, there has been a radical change in dromedary camel farming practices in the Arabian Peninsula with an intensification of the production and a concentration of the production around cities. It is possible that the recent intensification of camel herding in the Arabian Peninsula has increased the virus' reproductive number and attack rate in camel herds while the ‘urbanization’ of camel herding increased the frequency of zoonotic ‘spillover’ infections from camels to humans. It is reasonable to assume, although difficult to measure, that the sensitivity of public health surveillance to detect previously unknown diseases is lower in East Africa than in Saudi Arabia and that sporadic human cases may have gone undetected there.
Databáze: OpenAIRE
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