Nanotechnology for Neuroscience: Promising Approaches for Diagnostics, Therapeutics and Brain Activity Mapping
Autor: | Joanna K L Wong, Jonathan Clayton Spagnoli, Jin Xie, Natasha G, Keyoumars Ashkan, Aaron Tan, Brianna Diane Blevins, Anil Kumar, James Lam, Lewis Thorne, Hong Liu |
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Rok vydání: | 2019 |
Předmět: |
0301 basic medicine
Materials science Brain activity and meditation media_common.quotation_subject Ion sensing Nanotechnology 02 engineering and technology 021001 nanoscience & nanotechnology Condensed Matter Physics Article Electronic Optical and Magnetic Materials Biomaterials 03 medical and health sciences 030104 developmental biology Electrochemistry 0210 nano-technology Function (engineering) Neural regeneration Neuroscience media_common |
Zdroj: | Advanced functional materials. 27(39) |
ISSN: | 1616-301X |
Popis: | Unlocking the secrets of the brain is a task fraught with complexity and challenge – not least due to the intricacy of the circuits involved. With advancements in the scale and precision of scientific technologies, we are increasingly equipped to explore how these components interact to produce a vast range of outputs that constitute function and disease. Here, an insight is offered into key areas in which the marriage of neuroscience and nanotechnology has revolutionized the industry. The evolution of ever more sophisticated nanomaterials culminates in network-operant functionalized agents. In turn, these materials contribute to novel diagnostic and therapeutic strategies, including drug delivery, neuroprotection, neural regeneration, neuroimaging and neurosurgery. Further, the entrance of nanotechnology into future research arenas including optogenetics, molecular/ion sensing and monitoring, and piezoelectric effects is discussed. Finally, considerations in nanoneurotoxicity, the main barrier to clinical translation, are reviewed, and direction for future perspectives is provided. |
Databáze: | OpenAIRE |
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