Subacute thyroiditis in a patient with psoriatic arthritis switched from secukinumab to adalimumab: a case report and literature review
| Autor: | Atsushi Kawakami, Akinari Mizokami, Keita Nakaji, Midori Akagi, Yumi Hanatani, Jun Nakagawa, K. Fujikawa, Toshihide Hara, Junichi Yasui |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Thyroid Gland Thyrotropin Thyroid Function Tests Antibodies Monoclonal Humanized Psoriatic arthritis medicine Adalimumab Humans Thyroiditis Subacute Aged Subacute thyroiditis Neck pain business.industry Arthritis Psoriatic Interleukin-17 Interleukin medicine.disease Dermatology Thyroxine Antirheumatic Agents Triiodothyronine Female Tumor Necrosis Factor Inhibitors Secukinumab medicine.symptom business medicine.drug |
| Zdroj: | Modern Rheumatology Case Reports. 5:36-39 |
| ISSN: | 2472-5625 |
| DOI: | 10.1080/24725625.2020.1741116 |
| Popis: | A 71-year-old Japanese female with psoriatic arthritis (PsA) was admitted for fever and neck pain. Her medication had been switched from secukinumab, an interleukin (IL)-17A inhibitor, to adalimumab, a tumour necrosis factor (TNF)-α inhibitor, due to secondary failure for PsA. She was diagnosed with subacute thyroiditis (SAT) on the basis of thyroid hormone levels and thyroid ultrasound findings. Her SAT symptoms improved with prednisolone administration (15 mg/day). Following the administration of ixekizumab, an IL-17A inhibitor, her PsA improved without SAT relapse. SAT mechanism associated with TNF inhibitors remains unknown, but cytokine imbalance may be involved. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|