Gender aspects in chronic myeloid leukemia: long-term results from randomized studies

Autor:	Andreas Reiter, T. Lahaye, Dieter K. Hossfeld, Hermann Heimpel, Wolfgang Queisser, Rüdiger Hehlmann, Markus Pfirrmann, O. Maywald, Ursula Berger, H. Pralle, Helmut Löffler, Andreas Hochhaus, Hans-Jochem Kolb, Joerg Hasford
Rok vydání:	2005
Předmět:	Adult Male Cancer Research medicine.medical_specialty Alpha interferon Antineoplastic Agents Gastroenterology Age Distribution Risk Factors hemic and lymphatic diseases Internal medicine Cause of Death Leukemia Myelogenous Chronic BCR-ABL Positive Antineoplastic Combined Chemotherapy Protocols medicine Humans Hydroxyurea Risk factor Sex Distribution Antineoplastic Agents Alkylating Busulfan Survival analysis Aged Sex Characteristics business.industry Myeloid leukemia Interferon-alpha Hematology Middle Aged medicine.disease Survival Analysis Surgery Transplantation Leukemia Treatment Outcome Oncology Female business medicine.drug Chronic myelogenous leukemia
Zdroj:	Leukemia. 19(6)
ISSN:	0887-6924
Popis:	Gender-related aspects in chronic myeloid leukemia (CML) have not been studied well. We therefore analyzed 856 patients with Ph/BCR-ABL-positive CML from the German randomized CML-studies I (interferon alpha (IFN) vs hydroxyurea (HU) vs busulfan) and II (IFN+HU vs HU alone). The median observation time was 8.6 years. A total of 503 patients (59%) were male. Female patients were older (51 vs 46 years; P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4b2fbc72250983df62209e72aa29c19 https://pubmed.ncbi.nlm.nih.gov/15830009 Zobrazit plný text záznamu Plný text ve formátu PDF