Improving the Waiting List by Using 75-Year-Old Donors for Recipients With Hepatocellular Carcinoma
| Autor: | Pablo Ramírez Romero, P. Parrilla Paricio, R. Robles Campos, P. Cascales Campos, J. de la Peña, Robinson G. Gonzalez, A. Sanmartin Monzo, J. Domingo, Manuel Miras, Antonio Ríos Zambudio, J. A. Pons Miñano, Francisco Sánchez Bueno, I.M. Martinez Frutos, V. Bixquert Montagud |
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| Rok vydání: | 2010 |
| Předmět: |
Liver Cirrhosis
Male Brain Death Pediatrics medicine.medical_specialty Carcinoma Hepatocellular Cirrhosis Waiting Lists medicine.medical_treatment Liver transplantation Milan criteria Gastroenterology Internal medicine medicine Humans Survival rate Aged Aged 80 and over Transplantation business.industry Patient Selection Liver Neoplasms Age Factors Transplant Waiting List Middle Aged medicine.disease Tissue Donors Tumor progression Waiting list Hepatocellular carcinoma Female Surgery business |
| Zdroj: | Transplantation Proceedings. 42:627-630 |
| ISSN: | 0041-1345 |
| DOI: | 10.1016/j.transproceed.2010.02.015 |
| Popis: | The best treatment for hepatocellular carcinoma (HCC) associated with liver cirrhosis is liver transplantation and the best results are obtained when the tumors fulfill the Milan criteria. However, although the number of transplants is increasing, the organ deficit is growing, which lengthens time on the waiting list, increasing the risk of tumor progression of and exclusion from the list. The use of elderly donors is a valid option for patients on the transplant waiting list with HCC, reducing time on the waiting list. We report our experience with patients transplanted for HCC associated with hepatic cirrhosis using livers from donors >75 years of age. Our preliminary results supported the use of elderly suboptimal donors making it possible to give priority to these patients. All patients in the series achieved good graft function after a follow-up of 2 years with a 100% disease-free survival rate. More extensive long-term studies are needed to confirm these findings. |
| Databáze: | OpenAIRE |
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