Circadian fluctuations in GFAP distribution in the Syrian hamster suprachiasmatic nucleus
| Autor: | Lavialle M, Servière J |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Male
medicine.medical_specialty Central nervous system Hamster macromolecular substances Biology 03 medical and health sciences Nerve Fibers 0302 clinical medicine Rhythm Cricetinae Internal medicine Glial Fibrillary Acidic Protein medicine Animals Circadian rhythm 030304 developmental biology 0303 health sciences Neuronal Plasticity Mesocricetus Suprachiasmatic nucleus General Neuroscience Darkness Immunohistochemistry Circadian Rhythm Endocrinology medicine.anatomical_structure nervous system Hypothalamus Neuroglia Suprachiasmatic Nucleus sense organs 030217 neurology & neurosurgery Astrocyte |
| Zdroj: | NeuroReport. 4:1243-1246 |
| ISSN: | 0959-4965 |
| DOI: | 10.1097/00001756-199309000-00008 |
| Popis: | We examined the possibility that astrocytes reflect mammalian circadian rhythmicity by observing the astrocytes pattern using anti-glial fibrillary acidic protein (GFAP), within the suprachiasmatic nucleus of the Syrian hamster over the 24 h cycle. Our results reveal daily systematic changes in the distribution of GFAP-immunoreactivity (GFAP-ir) both in the light/dark cycle and in constant darkness. This rhythm is characterized by a change of the GFAP-ir distribution from a network pattern to isolated cells. Such a rhythm is in synchrony with the rhythm in SCN glucose consumption which we have previously reported. This is the first time a circadian rhythm in suprachiasmatic astrocytes has been observed, indicating that GFAP-ir can be used as a novel index of clock activity. |
| Databáze: | OpenAIRE |
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