Severe ischemic bowel necrosis caused by terlipressin during treatment of hepatorenal syndrome

Autor: Sang Woo Lee, Hyung Joon Yim, Ja Young Ryu, Young-Sun Lee, Sung Woo Jung, Jai Hyun Choi, Sun Jae Lee, Eileen L. Yoon, Hyunjoo Lee, Hyun Jung Lee, Hae Rim Kim, Rok Sun Choung, Ja Seol Koo, Jong Jin Hyun
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: Clinical and Molecular Hepatology, Vol 19, Iss 4, Pp 417-420 (2013)
Clinical and molecular hepatology
ISSN: 2287-2728
Popis: Terlipressin is a vasopressin analogue that is widely used in the treatment of hepatorenal syndrome or variceal bleeding. Because it acts mainly on splanchnic vessels, terlipressin has a lower incidence of severe ischemic complications than does vasopressin. However, it can still lead to serious complications such as myocardial infarction, skin necrosis, or bowel ischemia. Herein we report a case of severe ischemic bowel necrosis in a 46-year-old cirrhotic patient treated with terlipressin. Although the patient received bowel resection, death occurred due to ongoing hypotension and metabolic acidosis. Attention should be paid to patients complaining of abdominal pain during treatment with terlipressin.
Databáze: OpenAIRE