Peripheral Artery Disease as a Predictor of Coronary Artery Disease in Patients Undergoing Coronary Angiography
| Autor: | Ahmed Ali, Simra Shahid, Shehar Bano, Jatender Kumar, Umama Bhurgri, Love Kumar, Amber Rizwan, Suman Dembra, Ashok Kumar, Dua Khalid |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Cardiology Disease 030204 cardiovascular system & hematology peripheral artery disease Coronary artery disease 03 medical and health sciences 0302 clinical medicine Internal medicine Internal Medicine Medicine angiography cardiovascular diseases predictive tool medicine.diagnostic_test business.industry Unstable angina General Engineering medicine.disease Confidence interval body regions Stenosis medicine.anatomical_structure Coronary vessel Angiography Ankle business 030217 neurology & neurosurgery coronary artery disease |
| Zdroj: | Cureus |
| ISSN: | 2168-8184 |
| Popis: | Background Peripheral artery disease (PAD) may be a useful tool to predict coronary artery disease (CAD) in patients undergoing coronary angiography. If proven that PAD can be a good predictor of CAD, it can help in early and cost-effective diagnosis of CAD. Methodology This observational study was conducted from January 2020 to February 2021 in the cardiology unit of a tertiary care hospital. Participants older than 40 years, with a history of uncontrolled hypertension and unstable angina, who warranted the need of angiography were enrolled in study. After enrollment and recording history, these cases were assessed for the presence of PAD based on ankle brachial index (ABI). ABI values less than 0.9 were labelled as participants with PAD. Then these cases underwent coronary angiography at the same institute, and the presence of greater than 50% stenosis of any coronary vessel on angiography was taken as positive CAD. Results In this study, PAD was identified in 152 (62.8%) participants. A total of 165 (68.1%) participants had greater than 50% stenosis on angiography. Out of 152 participants with ABI less than 0.9, 140 had greater than 50% stenosis on angiography. In total, 90 participants had ABI more than 0.9, of which 35 participants had greater than 50% stenosis. Sensitivity of PAD in predicting coronary artery stenosis was 80.0% (95% confidence interval [CI]: 73.30%-85.66%), specificity was 82.09% (95% CI: 70.80%-90.39%), and accuracy was 80.58% (95% CI: 75.02%-85.37%). Conclusions Our study demonstrated that the sensitivity, specificity, and accuracy of PAD in predicting coronary artery stenosis were significant. Hence, we conclude that PAD can be an excellent predictor of CAD by helping in early and cost-effective diagnosis of CAD. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|