Multiple Immune Abnormalities in a Patient with Idiopathic CD4+ T-Lymphocytopenia
| Autor: | Osamu Hano, Yasuaki Yamada, Kunihiro Tsukasaki, Masahiko Okada, Shimeru Kamihira, Kazuto Tsuruda, Katsunori Yanagihara, Masanori Yanai, Hiroo Hasegawa, Hiroyuki Moriuchi, Akira Kamitamari |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2009 |
| Předmět: |
Adult
Male business.industry Human immunodeficiency virus (HIV) T lymphocytopenia General Medicine medicine.disease medicine.disease_cause ICL CD4 Immune system Immune System Diseases New disease Immunology Internal Medicine medicine Humans CD4+ T-Lymphocytopenia T-Lymphocytopenia Idiopathic CD4-Positive business Generalized lymphadenopathy |
| Zdroj: | Internal Medicine. 48(22):1967-1971 |
| ISSN: | 0918-2918 |
| Popis: | Idiopathic CD4+ T-lymphocytopenia (ICL) is a new disease entity characterized by CD4+ T-lymphocyte depletion without evidence of HIV infection. We report a 27-year-old ICL patient with a long history of multiple immune abnormalities. His CD4+ T-lymphocyte count started to decrease after generalized lymphadenopathy of an unknown cause at age 3. He satisfied the criteria for ICL at age 9, and the decreased CD4+ Tlymphocyte count persisted for more than 18 years. This is probably the first childhood-onset ICL case in which the trigger event for the development was known together with the patient's autoimmune background. Internal Medicine, 48(22), pp.1967-1971; 2009 |
| Databáze: | OpenAIRE |
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