Systolic function in hypertensive men with concentric remodeling
| Autor: | David W. Williams, John S. Gottdiener, Domenic J. Reda, Diego B. Sadler, Barry J. Materson, Gerard P. Aurigemma |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Male
medicine.medical_specialty Heart disease Systole Systolic function Concentric Ventricular Function Left Muscle hypertrophy Internal medicine Internal Medicine Medicine Humans Mass index Obesity Aged business.industry Myocardium Stroke volume Middle Aged medicine.disease Myocardial Contraction Echocardiography Hypertension Cardiology business Wall thickness |
| Zdroj: | Hypertension (Dallas, Tex. : 1979). 30(4) |
| ISSN: | 0194-911X |
| Popis: | Abstract Hypertensive patients with concentric remodeling (relative wall thickness ≥0.45 and normal left ventricular [LV] mass index) may have poor outcomes. It is unclear whether systolic function abnormalities, shown to be present in some patients with concentric LV hypertrophy (increased LV mass index and relative wall thickness ≥0.45), are also present in patients with concentric remodeling. To assess LV pump, chamber, and myocardial function in hypertensive men with concentric remodeling, clinical and echocardiographic data of 118 hypertensive men with concentric remodeling were compared with data from 104 hypertensive men with normal relative wall thickness and normal LV mass index. Chamber function was assessed by relating endocardial fractional shortening to end-systolic circumferential stress, myocardial function was assessed by relating midwall fractional shortening to circumferential stress, and pump performance was assessed by stroke volume (Teichholz method). Compared with hypertensive men with normal relative wall thickness, concentric-remodeling patients had lower stroke volume (84±20 versus 111±20 mL, P P =NS), but midwall shortening was lower in patients with concentric remodeling (20±3% versus 22±3%, P 2 , P |
| Databáze: | OpenAIRE |
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