The impact of chronic kidney disease on outcomes following peripheral vascular intervention

Autor: William S Jones, George L. Adams, Ehrin J. Armstrong, William A. Gray, Jihad Mustapha, Eric A. Secemsky, Dennis I. Narcisse, Gary M. Ansel, Elizabeth Hope Weissler, Manesh R. Patel, Jennifer A. Rymer
Rok vydání: 2020
Předmět:
Zdroj: Clinical Cardiology
ISSN: 1932-8737
0160-9289
DOI: 10.1002/clc.23444
Popis: BACKGROUND Patients with chronic kidney disease (CKD) have worsened clinical outcomes following percutaneous coronary intervention; however, limited evidence exists in patients undergoing peripheral vascular intervention (PVI). PURPOSE We aimed to assess the effect of CKD on outcomes following PVI for symptomatic peripheral artery disease. METHODS Using patients from the LIBERTY 360 study, we compared the rates of 30 day and 1 year major adverse vascular events (MAVE), a composite of all-cause mortality, major amputation, and target vessel/lesion revascularization, between patients with and without CKD (estimated glomular filtration rate less than 60) following PVI. Multivariable adjustment was performed to assess for independent association between CKD and outcomes. RESULTS Among 1189 patients enrolled, 378 patients (31.8%) had CKD. At 1 year, patients with CKD had higher rates of MAVE (34.6% vs 25.6%), all-cause mortality (11.9% vs 5.5%), and major amputation (5.9% vs 2.6%) when compared with patients without CKD (all P
Databáze: OpenAIRE