Cryptococcal meningitis presenting with bilateral complete ophthalmoplegia: a case report
| Autor: | Priyankara Perera, Damith S Liyanage, Lakmini P S Pathberiya, Ranjani Gamage, Manjula Chandragomi Caldera, Inuka Kishara Gooneratne |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Pathology Complete ophthalmoplegia Eye Diseases Opportunistic infection Case Report Meningitis Cryptococcal Asymptomatic General Biochemistry Genetics and Molecular Biology Cerebrospinal fluid medicine Humans Medicine(all) Cryptococcus neoformans Thalamic lesions biology medicine.diagnostic_test Biochemistry Genetics and Molecular Biology(all) business.industry Cranial nerves Magnetic resonance imaging General Medicine biology.organism_classification medicine.disease Magnetic Resonance Imaging Surgery medicine.symptom business Cryptococcal meningitis |
| Zdroj: | BMC Research Notes |
| ISSN: | 1756-0500 |
| Popis: | Background Cryptococcus neoformans is saprophytic encapsulated yeast. Infection is acquired by inhalation of the organism and could be asymptomatic or limited to the lungs, specially in the immunocompetent host. Cryptococcal meningitis is a serious opportunistic infection among post transplant recipients. Cranial nerve palsies and ophthalmoplegia are well known complications of this disease, but bilateral complete ophthalmoplegia is a very rare presentation. Case Presentation A Sri Lankan young male, who is a post kidney transplant recipient, presented with bilateral complete ophthalmoplegia and subsequently was diagnosed to have cryptococcal meningitis based on Indian ink stain and culture of cerebrospinal fluid (CSF). His magnetic resonance imaging (MRI) showed bilateral multiple nodular lesions in both basal ganglia and thalami. Brainstem imaging was normal. Conclusions Cryptococcal meningitis is a serious fungal infection in post transplant patients. It should be suspected in any immunocompromised patient with fever, headache and focal neurological signs. Bilateral thalamic lesions, inflammation and invasion of the cranial nerves and raised intracranial pressure were thought to be possible mechanisms resulting in bilateral complete ophthalmoplegia in this patient. |
| Databáze: | OpenAIRE |
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