The role of trimethylamine-N-oxide level in the diagnosis of diabetic retinopathy and the differential diagnosis of diabetic and nondiabetic retinopathy

Autor:	Burkay, Yakar, Erhan, Onalan, Tugce, Kaymaz, Emir, Donder, Mehmet Ferit, Gursu
Rok vydání:	2022
Předmět:	Ophthalmology Diabetic retinopathy Type 2 diabetes mellitus Trimethylamine-N-oxide Differential diagnosis Oxides General Medicine Trimethyloxamine Biomarkers
Zdroj:	Arquivos Brasileiros de Oftalmologia n.ahead 2022 Arquivos brasileiros de oftalmologia Conselho Brasileiro de Oftalmologia (CBO) instacron:CBO
ISSN:	0004-2749
DOI:	10.5935/0004-2749.2021-0527
Popis:	Purpose: Trimethylamine N-oxide serum levels have been associated with type 2 diabetes mellitus and its complications. The current study aimed to find out if plasma trimethylamine N-oxide level may be a novel marker in the diagnosis of diabetic retinopathy and if it can be used in the differential diagnosis of diabetic and nondiabetic retinopathy. Methods: The study included 30 patients with diabetic retinopathy, 30 patients with nondiabetic retinopathy, 30 patients with type 2 diabetes mellitus without retinopathy, and 30 healthy control participants. Biochemical parameters, serum IL-6, TNF-α, and trimethylamine N-oxide levels were measured in all participants. Results: Trimethylamine N-oxide level was significantly higher in diabetic retinopathy than in the other groups (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e48a0333e1141da232818b63b6f391db https://doi.org/10.5935/0004-2749.2021-0527 Zobrazit plný text záznamu