| Autor: |
Stephen I. Pelton, Brent A Little, Kimberly M. Shea, Julianne Meehan |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
Open Forum Infectious Diseases |
| ISSN: |
2328-8957 |
| Popis: |
Background Detecting Streptococcus pneumoniae (SP) carriage in children via conventional microbiological methods lacks sensitivity as high density is required for routine culture and identification of dual serotype colonization is a technical challenge. To increase understanding of post vaccine nasopharyngeal (NP) carriage, specifically persistence of vaccine serotypes, strategies for molecular identification of SP have been developed. These methods most often rely on the identification of the SP autolysin gene lytA through non-quantitative PCR or semi-quantitative real-time PCR (RTPCR). Methods We collected NP swabs from 600 healthy or sick children |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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