Phenylalanine and Tyrosine in the Adrenal Medulla
| Autor: | G. Thieme, Nils-Åke Hillarp, Gösta Hall |
|---|---|
| Rok vydání: | 1961 |
| Předmět: |
chemistry.chemical_classification
medicine.medical_specialty Biochemical Phenomena Physiology Phenylalanine Amino acid Endocrinology medicine.anatomical_structure chemistry Biochemistry Adrenal Medulla Internal medicine Blood plasma medicine Catecholamine Tyrosine Adrenal medulla Phenylalanine metabolism Tyrosine Metabolism medicine.drug |
| Zdroj: | Acta Physiologica Scandinavica. 52:49-52 |
| ISSN: | 1365-201X 0001-6772 |
| DOI: | 10.1111/j.1748-1716.1961.tb02199.x |
| Popis: | The claim (Fellman 1958, Fellman and Devlin 1958) that large amounts of free phenylalanine are present in the adrenal medulla has been tested using cation exchange and paper chromatographic methods. The concentration of this amino acid was found to be very low (< 20 to 40 μg/g wet wt). Tyrosine — but no m-tyrosine, phenylserine or 3,4-dihydroxyphenylalanine (< 20 μg/g) – was detected in small amounts (10 to 20 μg/g). Thus the catecholamine producing cells in the gland do not accumulate free phenylalanine or tyrosine to a level appreciably higher than that in the blood plasma. |
| Databáze: | OpenAIRE |
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