Cytotoxic steroidal glycosides from the rhizomes of Paris polyphylla var. yunnanensis

Autor:	Yang Liu, Mei-You Liu, Lin-Lin Bi, Yun-Yuan Tian, Peng-Cheng Qiu, Xiao-Ying Qian, Min-Chang Wang, Hai-Feng Tang, Yun-Yang Lu, Bang-Le Zhang
Rok vydání:	2022
Předmět:	Plant Science General Medicine Horticulture Molecular Biology Biochemistry
Zdroj:	Phytochemistry. 207
ISSN:	1873-3700
Popis:	Paris polyphylla var. yunnanensis (Franch.) Hand.-Mazz. (Melanthiaceae), an important specie of the genus Paris, has long been in a traditional Chinese medicine (TCM) for a long time. This study aimed to isolate and identify the structures of bioactive saponins from the rhizomes of P. polyphylla var. yunnanensis and evaluate their cytotoxicity against BxPC-3, HepG2, U373 and SGC-7901 carcinoma cell lines. Seven previously undescribed and seven known saponins were identified, and Paris saponins VII (PSVII) showed significant cytotoxicity against the BxPC-3 cell line with IC
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4799e07e1885352dff04c6c8938ebd4 https://pubmed.ncbi.nlm.nih.gov/36587887 Zobrazit plný text záznamu Full Text from ScienceDirect