Advanced carbon dots via plasma-induced surface functionalization for fluorescent and bio-medical applications
| Autor: | Ha-Rim An, Heeyoung Yang, Hyun Uk Lee, Jong-Pil Kim, Hee Sik Kim, Saehae Choi, Yunju Choi, Hyeran Kim, Edmond Changkyun Park, Che Yoon Lee, Hyun Gyu Park, Kyoung Suk Kang, So Young Park, Young-Chul Lee, Jouhahn Lee, Hang-Suk Chun |
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| Rok vydání: | 2017 |
| Předmět: |
Acinetobacter baumannii
Materials science Plasma Gases Biocompatibility Quantum yield Atmospheric-pressure plasma Nanotechnology 02 engineering and technology Polyethylene glycol 010402 general chemistry 01 natural sciences Fluorescence Polyethylene Glycols chemistry.chemical_compound Cell Line Tumor Materials Testing Quantum Dots Escherichia coli Animals Humans General Materials Science Cytotoxicity Zebrafish 021001 nanoscience & nanotechnology Carbon humanities Anti-Bacterial Agents 0104 chemical sciences chemistry Surface modification Nanodot Reactive Oxygen Species 0210 nano-technology Nuclear chemistry |
| Zdroj: | Nanoscale. 9:9210-9217 |
| ISSN: | 2040-3372 2040-3364 |
| DOI: | 10.1039/c7nr03026f |
| Popis: | Multifunctional carbon-based nanodots (C-dots) are synthesized using atmospheric plasma treatments involving reactive gases (oxygen and nitrogen). Surface design was achieved through one-step plasma treatment of C-dots (AC-paints) from polyethylene glycol used as a precursor. These AC-paints show high fluorescence, low cytotoxicity and excellent cellular imaging capability. They exhibit bright fluorescence with a quantum yield twice of traditional C-dots. The cytotoxicity of AC-paints was tested on BEAS2B, THLE2, A549 and hep3B cell lines. The in vivo experiments further demonstrated the biocompatibility of AC-paints using zebrafish as a model, and imaging tests demonstrated that the AC-paints can be used as bio-labels (at a concentration of 1 mg mL−1). AC-paints can effectively inhibit the growth of Escherichia coli (E. coli) and Acinetobacter baumannii (A. baumannii). Such remarkable performance of the AC-paints has important applications in the biomedical field and environmental systems. |
| Databáze: | OpenAIRE |
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