Twitch mouth pressure for detecting respiratory muscle weakness in suspicion of neuromuscular disorder
| Autor: | Gilbert Desmarais, Frédéric Lofaso, Dante Brasil Santos, Sandrine Cognet, Bruno Louis, L. Falaize, Hélène Prigent, Adam Ogna, David Orlikowski |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty Weakness Neuromuscular disease Diaphragm Diaphragmatic breathing Stimulation Sensitivity and Specificity 03 medical and health sciences Esophagus 0302 clinical medicine Internal medicine Pressure medicine Humans Respiratory muscle weakness Genetics (clinical) Mouth Muscle Weakness business.industry Muscle weakness Neuromuscular Diseases Middle Aged musculoskeletal system medicine.disease Nasal pressure Respiratory Muscles Respiratory Function Tests Surgery Phrenic Nerve Inhalation 030228 respiratory system Neurology Mouth pressure Pediatrics Perinatology and Child Health Cardiology Female Neurology (clinical) medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | Neuromuscular Disorders. 27:518-525 |
| ISSN: | 0960-8966 |
| DOI: | 10.1016/j.nmd.2017.01.022 |
| Popis: | Twitch mouth pressure using magnetic stimulation of the phrenic nerves and an automated inspiratory trigger is a noninvasive, non-volitional assessment of diaphragmatic strength. Our aims were to validate this method in patients with suspected neuromuscular disease, to determine the best inspiratory-trigger pressure threshold, and to evaluate whether twitch mouth pressure decreased the overdiagnosis of muscle weakness frequently observed with noninvasive volitional tests. Maximal inspiratory pressure, sniff nasal pressure, and twitch mouth pressure were measured in 112 patients with restrictive disease and suspected neuromuscular disorder. Esophageal and transdiaphragmatic pressures were measured in 64 of these patients to confirm or infirm inspiratory muscle weakness. Magnetic stimulation was triggered by inspiratory pressures of −1 and −5 cmH2O. The −5 cmH2O trigger produced the best correlation between twitch mouth pressure and twitch esophageal pressure (R2 = 0.86; P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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