Incidence of congestive heart failure in rheumatoid arthritis: a review of literature and meta‐regression analysis
| Autor: | Alan Kaell, Keith Brown, Neethi R. Dasu, Kirti Dasu, Yaser Khalid, Adam Levine, Albert Raminfard, Ankit Shah |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Congestive heart failure
medicine.medical_specialty Population Disease 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Female gender Inflammatory disorder Internal medicine Diabetes mellitus Original Research Articles Medicine Diseases of the circulatory (Cardiovascular) system 030212 general & internal medicine Original Research Article Rheumatoid arthritis education education.field_of_study business.industry Incidence (epidemiology) Odds ratio medicine.disease Cardiovascular disease Confidence interval Heart failure RC666-701 Cardiology and Cardiovascular Medicine business |
| Zdroj: | ESC Heart Failure, Vol 7, Iss 6, Pp 3745-3753 (2020) ESC Heart Failure |
| ISSN: | 2055-5822 |
| Popis: | Aims Rheumatoid arthritis (RA) is a systemic inflammatory autoimmune disorder that not only affects peripheral joints but also increases the risk for cardiovascular disease (CVD) and mortality. Heart failure (HF) appears to be one of the most important contributors to the excess mortality risk among patients with RA. We assessed the incidence of HF in patients with RA compared with age‐matched and sex‐matched non‐RA subjects, after accounting for traditional cardiovascular risk factors and clinical ischemic heart disease. Methods and results We performed an aggregate analysis on three studies of RA patients having listed manifestations of HF. We performed a meta‐regression analysis to evaluate the incidence of HF in RA patients with increased age and noted for any gender correlation. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using both fixed‐effects and random‐effects models. In the cumulative analysis of 5, 220, 883 patients, the incidence of HF was noted to be almost two‐fold higher in patients with RA compared with a matched control population (OR 1.78, 95% CI 1.22–2.60, P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text