Development and validation of a bladder trabeculation grading system in pediatric neurogenic bladder
| Autor: | Tandis Soltani, Antoine E. Khoury, Elias Wehbi, John Billimek, Blake Selby, Kai-wen Chuang, Guy Hidas, Sherrie H. Kaplan |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Observer Variation
medicine.medical_specialty Future studies Cystography business.industry Urology education 030232 urology & nephrology Urinary Bladder Diseases Reproducibility of Results Pediatric urology Bladder trabeculation 03 medical and health sciences 0302 clinical medicine 030225 pediatrics Pediatrics Perinatology and Child Health medicine Humans Radiology Urinary Bladder Neurogenic business Child Kappa Reliability (statistics) Face validity |
| Zdroj: | Journal of pediatric urology. 16(3) |
| ISSN: | 1873-4898 |
| Popis: | Bladder trabeculation (BT) is commonly noted on cystogram images of patients with neurogenic bladder (NB). BT is associated with a hostile bladder often requiring prompt, more aggressive management. We aimed to define and validate a reliable grading system for BT severity. The proposed grading system will improve clinicians and radiologist's communication and serve as a foundation for future studies in the field of NB. The study was conducted in two phases: 1) Development of a grading system for BT and 2) testing of the proposed grading system for reliability and validity. Agreement between raters was assessed using Cohen's Kappa. Inter-rater reliability and intra-rater reliability was assessed using intra-class correlation coefficients (ICC) and Spearman's p (rho) correlation coefficient. The content of the grading system was assessed for face validity by senior pediatric urology and radiology experts. We observed inter-rater reliability with ICC of 0.998 (95%CI 0.996-0.999, p 0.001), and a Cohen's Kappa ranging from 0.795 to 1.0, p 0.001 and Spearman's p (rho) correlation coefficient ranging from 0.910 to 1.0, p 0.001 between raters on the decided grades of BT. In conclusion, we established a defined grading system for BT severity that has substantial inter/intra-rater reliability and validity. This grading system could be useful for improving clinician and radiologist's communication about the status of a child's bladder wall and serve as a foundation for future studies assessing severity of NB. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect