Natural language processing for structuring clinical text data on depression using UK-CRIS
Autor: | Ayse Kurtulmus, Qiang Liu, Franco De Crescenzo, Nemanja Vaci, Andrea Cipriani, Anneka Tomlinson, Alejo J. Nevado-Holgado, Jade Harvey, Andrey Kormilitzin, Bessie O'Dell, Simeon Innocent |
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Rok vydání: | 2019 |
Předmět: |
Relation (database)
Computer science computer.software_genre Structuring 03 medical and health sciences 0302 clinical medicine Data Mining Electronic Health Records Humans 030212 general & internal medicine Natural Language Processing Depressive Disorder Models Statistical business.industry Depression Statistical model Mental health Pipeline (software) United Kingdom Psychiatry and Mental health Salient Active learning Key (cryptography) Feasibility Studies Artificial intelligence business computer 030217 neurology & neurosurgery Natural language processing |
Zdroj: | Evidence-based mental health. 23(1) |
ISSN: | 1468-960X |
Popis: | BackgroundUtilisation of routinely collected electronic health records from secondary care offers unprecedented possibilities for medical science research but can also present difficulties. One key issue is that medical information is presented as free-form text and, therefore, requires time commitment from clinicians to manually extract salient information. Natural language processing (NLP) methods can be used to automatically extract clinically relevant information.ObjectiveOur aim is to use natural language processing (NLP) to capture real-world data on individuals with depression from the Clinical Record Interactive Search (CRIS) clinical text to foster the use of electronic healthcare data in mental health research.MethodsWe used a combination of methods to extract salient information from electronic health records. First, clinical experts define the information of interest and subsequently build the training and testing corpora for statistical models. Second, we built and fine-tuned the statistical models using active learning procedures.FindingsResults show a high degree of accuracy in the extraction of drug-related information. Contrastingly, a much lower degree of accuracy is demonstrated in relation to auxiliary variables. In combination with state-of-the-art active learning paradigms, the performance of the model increases considerably.ConclusionsThis study illustrates the feasibility of using the natural language processing models and proposes a research pipeline to be used for accurately extracting information from electronic health records.Clinical implicationsReal-world, individual patient data are an invaluable source of information, which can be used to better personalise treatment. |
Databáze: | OpenAIRE |
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