La Sota vaccination may not protect against virus shedding and the lesions of velogenic Newcastle disease in commercial turkeys

Autor: Boniface M. Anene, ObianujuNkiruka Okoroafor, Paul Chekwube Eze, Chika Nwosu, P. C. Animoke, John Osita Arinze Okoye, Christian O. Okorie-Kanu, W. S. Ezema
Rok vydání: 2017
Předmět:
Zdroj: Tropical Animal Health and Production. 50:345-351
ISSN: 1573-7438
0049-4747
Popis: The aim of this project is to study the clinical signs and lesion of velogenic Newcastle disease (vND) in commercial turkeys, and also to find out if La Sota vaccination offered protection against these signs and lesions. The cockerels were included as positive controls. One hundred and twenty turkey poults and cockerels were divided into eight groups as follows: unvaccinated unchallenged turkeys (UUT), unvaccinated challenged turkeys (UCT), vaccinated unchallenged turkeys (VUT), vaccinated challenged turkeys (VCT), and along the same lines, the cockerel groups were UUC, UCC, VUC and vaccinated challenged cockerels (VCC). Vaccination was at 3 weeks of age while challenge was at 6 weeks of age. The unvaccinated turkeys and cockerels (UCT and UCC) showed different degrees of depression, diarrhoea and later paralysis at challenge. Total mortality was 100% in cockerels within 6 days, but 60% in turkeys. Similar but milder clinical signs were found in the VCC with a total mortality of 13.3%. The VCT showed mild drop in feed and water consumption, and no mortality. All the challenged groups had significant (p
Databáze: OpenAIRE