Adaptation of the cardiovascular system to postinfarction cardiosclerosis in rats with congenital adrenoreactivity of the myocardium
| Autor: | M. A. Usacheva, Popkova Ev, L. M. Belkina, E. A. Smirnova, V. A. Saltykova |
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| Rok vydání: | 2007 |
| Předmět: |
Cardiac function curve
medicine.medical_specialty Epinephrine Myocardial Infarction Scars Adrenergic General Biochemistry Genetics and Molecular Biology Catecholamines Species Specificity Internal medicine Receptors Adrenergic beta Animals Medicine Myocardial infarction Rats Wistar Sclerosis business.industry Mortality rate Rats Inbred Strains General Medicine medicine.disease Rats Heart failure cardiovascular system Cardiology Myocardial infarction complications medicine.symptom business medicine.drug |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 144:775-779 |
| ISSN: | 1573-8221 0007-4888 |
| Popis: | Three months after myocardial infarction the severity of heart failure and size of postinfarction scars in August rats with inherently reduced adrenoreactivity of the myocardium were similar to those in Wistar rats. The mortality rate in August rats was 2.5-fold lower than in Wistar rats. During the postinfarction period, myocardial adrenoreactivity in August rats remained lower, while the efficiency of cardiac function was 62% higher than in Wistar rats. The incidence of epinephrine-induced arrhythmias in August rats was much lower than in Wistar rats. |
| Databáze: | OpenAIRE |
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